منابع مشابه
Baclofen overdose.
A 57-year-old woman suffering from multiple sclerosis took an estimated 1500 mg of baclofen. She became deeply unconscious with generalized flaccid muscle paralysis and absent tendon reflexes. Toxicological analysis confirmed the presence of baclofen together with small amounts of paracetamol and glutethimide. Supportive therapy, including assisted ventilation for 3 days, led to complete recove...
متن کاملBaclofen-induced Psychosis in a Patient with Alcohol Dependence.
Baclofen became popular when cardiologist Olivier Ameisen described complete and prolonged suppression of symptoms and consequences of alcohol-dependence upon the use of high-dose baclofen in a self-case report (Ameisen 2005). In 2012, baclofen was approved by the AFSSAPS (Agence française de sécurité sanitaire des produits de santé French Agency for the Safety of Health Products) for use in th...
متن کاملGraphogenic epilepsy: a variant of language-induced epilepsy distinguished from reading- and praxis-induced epilepsy
We report a case of graphogenic epilepsy as a variant of language-induced epilepsy. A 25-year-old, right-handed woman had noticed for the previous 10 years that writing almost always provoked jerks or a jerking sensation in her right hand. No other triggers, including facets of language function such as reading and speaking, elicited any epileptic seizures. Ictal EEG demonstrated an initial lef...
متن کاملLife-threatening constipation induced by intrathecal baclofen therapy.
drugs (4 azathioprine, 2 methotrexate, 1 interferon beta-1b, 8 gabapentin, 2 pregabalin, 2 phenobarbital, 2 paroxetine, 1 citalopram, 1 venlafaxine, 7 furosemide, 4 heparin, 1 risperidone and 1 olanzapine). Fifteen patients did not receive any concomitant medication. ITB was administered with a mean effective daily dose of 251.3 8 11 g (range 90–580 g). Adverse events of ITB were monitored by e...
متن کاملBaclofen-Induced Encephalopathy in End Stage Renal Disease
Baclofen is a highly used centrally acting GABA agonist that continues to be an effective therapy for spasticity and chronic hiccups. The renally dependent excretion determines the circulating concentrations and guides effective dosing to decrease adverse reactions. Caution should be considered in administering baclofen to patients with decreased renal function. We present a patient with end st...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1990
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107689008300220